Resources

Interested in Learning Health Systems or becoming a part of the program? Please see the resources below for relevant information. Check back often as these will be updated regularly.

Search Tools

  • The PDQ-Evidence for Informed Health Policymaking allows you to search research terms and get immediate access to evidence for informing health decisions. Results include articles, systematic reviews, and other evidence: https://www.pdq-evidence.org/

Complex Interventions

  • Guise JM, Chang C, Viswanathan M, Glick S, Treadwell J, Umscheid C, Whitlock E, Fu R, Berliner E, Paynter R, Anderson J, Motu'apuaka M, Trikalinos T. Systematic Reviews of Complex Multicomponent Health Care Interventions. Research White Paper. AHRQ Publication No. 14-EHC003-EF. Rockville, MD: Agency for Healthcare Research and Quality. March 2014. www.effectivehealthcare.ahrq.gov/reports/final.cfm.

  • Guise JM, Tugwell P, Viswanathan M, on behalf of the Complex Interventions Working Group. AHRQ series on complex intervention systematic reviews-paper 6: PRISMA-CI extension statement and checklist. J Clin Epidemiol. 2017;90:43-50. PMID: 28720516

  • Guise JM, Butler M, Chang C, Viswanathan M, Hernán MA, Pigott T, Tugwell P, for the Complex Interventions Workgroup. AHRQ series on complex intervention systematic reviews-paper 7: PRISMA-CI elaboration and explanation. J Clin Epidemiol. 2017: 90:51-58. PMID: 28720513

  • Shaw D, Guise JM, Shah N, Guilherme C, DeLong J. Lancet Series on Maternal Health II: Drivers of maternity care in high-income countries: can health systems support woman-centred care? Lancet. 2016:388(10057):2282-2295. PMID: 27690340

Evidence-based Practice

  • Bennett WL, Pitts S, Aboumatar H, Sharma R, Smith BM, Das A, Day J, Holzhauer K, Bass EB. Strategies for Patient, Family and Caregiver Engagement. Technical Brief. (Prepared by the Johns Hopkins University Evidence-based Practice Center under Contract No. 290-2015-00006-I.) AHRQ Publication No. 20-EHC017. Rockville, MD: Agency for Healthcare Research and Quality; August 2020. DOI: 10.23970/AHRQEPCTB36

  • Schoelles K, Umscheid CA, Lin JS, Concannon TW, Skelly AC, Viswanathan M, Chang C, Kato E, Bass E, Lavenberg J, Peterson K, Newton A, Meyers E, Springs S, Christensen V, Floyd N, Fiordalisi C, Guise JM, Murad MH. A Framework for Conceptualizing Evidence Needs of Health Systems. Research White Paper. (Prepared by Scientific Resource Center, under Contract No. 290-2012-0004-C). AHRQ Publication No. 18-EHC004-EF. Rockville, MD: Agency for Healthcare Research and Quality. PMID: 29708677

  • White CM, Sanders Schmidler GD, Borsky A, Butler M, Wang Z, Robinson K, Mitchell MD, Berkman N, Henderson J, Fiordalisi C, Hartling L, Newberry SJ, Guise J-M, Niebuhr D, Pham D, Gozu A, Iyer S, Banez L. Understanding Health-Systems’ Use of and Need for Evidence To Inform Decisionmaking. Research White Paper. (Prepared by the University of Connecticut and Duke Evidence-based Practice Centers under Contract No. 290-2015-00012-I and 290-2015-00004-I.) AHRQ Publication No. 17(18)-EHC035-EF. Rockville, MD: Agency for Healthcare Research and Quality; October 2017.  PMID 29611913

High Value Healthcare Collaborative:

  • Savitz LA and LT Weiss. “A Data Driven Approach to Achieving High Value Healthcare.” eGEMs (Generating Evidence & Methods to improve patient outcomes), 5(3):1, 2017. http://doi.org/10.5334/egems.241

  • Welch G, F von Recklinghausen, A Taenzer, L Savitz and L Weiss. “Data Cleaning in the Evaluation of a Multi-Site Intervention Project.” eGEMs (Generating Evidence & Methods to improve patient outcomes), 5(3):4, 2017. http://doi.org/10.5334/egems.196

  • Taenzer A, A Kinslow, C Gorman, S Schoepflin Sanders, SJ Patel, S Kraft and L Savitz. “Dissemination and Implementation of Evidence Based Best Practice Across the High Value Healthcare Collaborative (HVHC) Using Sepsis as a Prototype – Rapidly Learning from Others.”. eGEMs (Generating Evidence & Methods to improve patient outcomes), 5(3):5, 2017. http://doi.org/10.5334/egems.192

  • Albritton J, T Belnap and L Savitz. “The Effect of the Hospital Readmission Reduction Program on the Duration of Observation Stays: Using Regression Discontinuity to Estimate Causal Effects.” eGEMs (Generating Evidence & Methods to improve patient outcomes), 5(3):6, 2017. http://doi.org/10.5334/egems.197

Learning Health Systems Science:

  • Budrionis A, Bellika JG. The Learning Healthcare System: Where are we now? A systematic review. J Biomed Inform 2016 Dec; 64:87-92.

  • Garvin DA, Edmondson AC, Gino F. Is yours a learning organization? Harv Bus Rev 2008 Mar; 86(3):109-16, 134.

  • Garvin DA. Building a learning organization. Harv Bus Rev 1993 Jul-Aug; 71(4):78-91.

  • Grant RW, Schmittdiel JA. Building a career as a delivery science researcher in a changing

    health care landscape. J Gen Intern Med 2015 Jul; 30(7):880-2.

  • Kanani N, EE Hahn, MK Gould, KD Brunisholz, Savitz LA and EC Holve. “AcademyHealth’s Delivery System Science Fellowship: Training embedded researchers to design, implement, and evaluate new models of care.” J Hosp Med, 12(7):570-574, Jul, 2017.

  • Lieu TA, Madvig PR. Strategies for building delivery science in an integrated health care

    system. J Gen Intern Med 2019 Jan 25. [Epub 2019 Jan 25]

LHS: Electronic Data Methods Forum, an AcademyHealth initiative funded by AHRQ:

  • Stoto M, M Oakes, E Stuart, L Savitz, EL Priest and J Zurovac. “Analytical Methods for a Learning Health System: 1. Framing the Research Question.” eGEMs (Generating Evidence & Methods to improve patient outcomes), 5(1):28, 2017. http://doi.org/10.5334/egems.250

  • Stoto M, M Oakes, E Stuart, EL Priest and L Savitz. “Analytical Methods for a Learning Health System: 2. Design of Observational Studies.” eGEMs (Generating Evidence & Methods to improve patient outcomes), 5(1):29, 2017. http://doi.org/10.5334/egems.251

  • Stoto M, Parry G, Savitz L. “Analytical Methods for a Learning Health System: 4. Delivery System Science”. eGEMs (Generating Evidence & Methods to improve patient outcomes). 2017;5(1):31. DOI: http://doi.org/10.5334/egems.253

LHS: Implementation and Healthcare Quality Improvement:

  • Atkins D, Kilbourne AM, Shulkin D. Moving from discovery to system-wide change: The role of research in a learning health care system: Experience from three decades of health systems research in the Veterans Health Administration. Annu Rev Public Health 2017 Mar 20; 38:467-487.

  • Churruca K, Ludlow K, Taylor N, Long JC, Best S, Braithwaite J. The time has come:

    Embedded implementation research for health care improvement. J Eval Clin Pract 2019 Jan 10. [Epub 2019 Jan 10]

  • Montori VM, Hargraves I, McNellis RJ, Ganiats TG, Genevro J, Miller T, Ricciardi R,

    Bierman AS. The care and learn model: A practice and research model for improving healthcare quality and outcomes. J Gen Intern Med 2019 Jan; 34(1):154-158.

  • Vindrola-Padros C, Pape T, Utley M, Fulop NJ. The role of embedded research in quality

    improvement: A narrative review. BMJ Qual Saf 2017 Jan; 26(1):70-80.

  • Schmittdiel JA, Grant RW. Crossing the research to quality chasm: A checklist for

    researchers and clinical leadership partners. J Gen Intern Med 2018 Jan; 33(1):9-10.

  • Vindrola-Padros C, Eyre L, Baxter H, Cramer H, George B, Wye L, Fulop NJ, Utley M,

    Phillips N, Brindle P, Marshall M. Addressing the challenges of knowledge co-production in quality improvement: Learning from the implementation of the researcher-in-residence model. BMJ Qual Saf 2019 Jan; 28(1):67-73.

Others:

  • Campbell EM, Li H, Mori T, Osterweil P, Guise JM. "“The Impact of Health Information Technology on Work Process and Patient Care in Labor and Delivery.” In: Henriksen K, Battles JB, Keyes MA, Grady ML, editors. Advances in Patient Safety: New Directions and Alternative Approaches (Vol. 4: Technology and Medication Safety). Rockville (MD): Agency for Healthcare Research and Quality (US); 2008 Aug. Adv Pat Safety.

  • Eden KB, Messina R, Li H, Osterweil P, Henderson CR, Guise JM. “Examining the Value of Electronic Health Records on Labor and Delivery.” Am J Obstet Gynecol, 199(3):307.e1-9.

  • Eriksson CO, Stoner RC, Eden KB, Newgard CD, Guise JM. “The Association Between Hospital Capacity Strain and Inpatient Outcomes in Highly Developed Countries: A Systematic Review.” J Gen Intern Med, 32(6):686-96.

  • Savitz LA and ST Savitz. “Can Delivery Systems Use Cost-Effectiveness Analysis to Reduce Healthcare Costs and Improve Value?” F1000 Research (an open science publishing platform), 5(F1000 Faculty Rev):2575, Oct, 2016. doi: 10.12688/f1000research.7531.1